Búsqueda | Biblioteca Virtual en Salud Fronteriza

1.

Early Alzheimer's disease pathology in human cortex involves transient cell states.

Gazestani, Vahid; Kamath, Tushar; Nadaf, Naeem M; Dougalis, Antonios; Burris, S J; Rooney, Brendan; Junkkari, Antti; Vanderburg, Charles; Pelkonen, Anssi; Gomez-Budia, Mireia; Välimäki, Nelli-Noora; Rauramaa, Tuomas; Therrien, Martine; Koivisto, Anne M; Tegtmeyer, Matthew; Herukka, Sanna-Kaisa; Abdulraouf, Abdulraouf; Marsh, Samuel E; Hiltunen, Mikko; Nehme, Ralda; Malm, Tarja; Stevens, Beth; Leinonen, Ville; Macosko, Evan Z.

Cell ; 186(20): 4438-4453.e23, 2023 09 28.

Artículo en Inglés | MEDLINE | ID: mdl-37774681

2.

GABA-receptive microglia selectively sculpt developing inhibitory circuits.

Favuzzi, Emilia; Huang, Shuhan; Saldi, Giuseppe A; Binan, Loïc; Ibrahim, Leena A; Fernández-Otero, Marian; Cao, Yuqing; Zeine, Ayman; Sefah, Adwoa; Zheng, Karen; Xu, Qing; Khlestova, Elizaveta; Farhi, Samouil L; Bonneau, Richard; Datta, Sandeep Robert; Stevens, Beth; Fishell, Gord.

Cell ; 184(15): 4048-4063.e32, 2021 07 22.

Artículo en Inglés | MEDLINE | ID: mdl-34233165

3.

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

Dolan, Michael-John; Therrien, Martine; Jereb, Sasa; Kamath, Tushar; Gazestani, Vahid; Atkeson, Trevor; Marsh, Samuel E; Goeva, Aleksandrina; Lojek, Neal M; Murphy, Sarah; White, Cassandra M; Joung, Julia; Liu, Bingxu; Limone, Francesco; Eggan, Kevin; Hacohen, Nir; Bernstein, Bradley E; Glass, Christopher K; Leinonen, Ville; Blurton-Jones, Mathew; Zhang, Feng; Epstein, Charles B; Macosko, Evan Z; Stevens, Beth.

Nat Immunol ; 24(8): 1382-1390, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37500887

4.

A Milieu Molecule for TGF-ß Required for Microglia Function in the Nervous System.

Qin, Yan; Garrison, Brian S; Ma, Wenjiang; Wang, Rui; Jiang, Aiping; Li, Jing; Mistry, Meeta; Bronson, Roderick T; Santoro, Daria; Franco, Charlotte; Robinton, Daisy A; Stevens, Beth; Rossi, Derrick J; Lu, Chafen; Springer, Timothy A.

Cell ; 174(1): 156-171.e16, 2018 06 28.

Artículo en Inglés | MEDLINE | ID: mdl-29909984

5.

Microglia and the Brain: Complementary Partners in Development and Disease.

Hammond, Timothy R; Robinton, Daisy; Stevens, Beth.

Annu Rev Cell Dev Biol ; 34: 523-544, 2018 10 06.

Artículo en Inglés | MEDLINE | ID: mdl-30089221

6.

GABA-receptive microglia selectively sculpt developing inhibitory circuits.

Favuzzi, Emilia; Huang, Shuhan; Saldi, Giuseppe A; Binan, Loïc; Ibrahim, Leena A; Fernández-Otero, Marian; Cao, Yuqing; Zeine, Ayman; Sefah, Adwoa; Zheng, Karen; Xu, Qing; Khlestova, Elizaveta; Farhi, Samouil L; Bonneau, Richard; Datta, Sandeep Robert; Stevens, Beth; Fishell, Gord.

Cell ; 184(22): 5686, 2021 Oct 28.

Artículo en Inglés | MEDLINE | ID: mdl-34715023

7.

Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts.

Loh, Ken H; Stawski, Philipp S; Draycott, Austin S; Udeshi, Namrata D; Lehrman, Emily K; Wilton, Daniel K; Svinkina, Tanya; Deerinck, Thomas J; Ellisman, Mark H; Stevens, Beth; Carr, Steven A; Ting, Alice Y.

Cell ; 166(5): 1295-1307.e21, 2016 Aug 25.

Artículo en Inglés | MEDLINE | ID: mdl-27565350

8.

Shedding light on glioma growth.

Lehrman, Emily K; Stevens, Beth.

Cell ; 161(4): 704-6, 2015 May 07.

Artículo en Inglés | MEDLINE | ID: mdl-25957677

9.

Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion.

Pinho-Ribeiro, Felipe A; Deng, Liwen; Neel, Dylan V; Erdogan, Ozge; Basu, Himanish; Yang, Daping; Choi, Samantha; Walker, Alec J; Carneiro-Nascimento, Simone; He, Kathleen; Wu, Glendon; Stevens, Beth; Doran, Kelly S; Levy, Dan; Chiu, Isaac M.

Nature ; 615(7952): 472-481, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36859544

10.

Immune Signaling in Neurodegeneration.

Hammond, Timothy R; Marsh, Samuel E; Stevens, Beth.

Immunity ; 50(4): 955-974, 2019 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-30995509

11.

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.

Hammond, Timothy R; Dufort, Connor; Dissing-Olesen, Lasse; Giera, Stefanie; Young, Adam; Wysoker, Alec; Walker, Alec J; Gergits, Frederick; Segel, Michael; Nemesh, James; Marsh, Samuel E; Saunders, Arpiar; Macosko, Evan; Ginhoux, Florent; Chen, Jinmiao; Franklin, Robin J M; Piao, Xianhua; McCarroll, Steven A; Stevens, Beth.

Immunity ; 50(1): 253-271.e6, 2019 01 15.

Artículo en Inglés | MEDLINE | ID: mdl-30471926

12.

Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.

Rueda-Carrasco, Javier; Sokolova, Dimitra; Lee, Sang-Eun; Childs, Thomas; Jurcáková, Natália; Crowley, Gerard; De Schepper, Sebastiaan; Ge, Judy Z; Lachica, Joanne I; Toomey, Christina E; Freeman, Oliver J; Hardy, John; Barnes, Samuel J; Lashley, Tammaryn; Stevens, Beth; Chang, Sunghoe; Hong, Soyon.

EMBO J ; 42(19): e113246, 2023 Oct 04.

Artículo en Inglés | MEDLINE | ID: mdl-37575021

13.

Neuron-Glia Signaling in Synapse Elimination.

Wilton, Daniel K; Dissing-Olesen, Lasse; Stevens, Beth.

Annu Rev Neurosci ; 42: 107-127, 2019 07 08.

Artículo en Inglés | MEDLINE | ID: mdl-31283900

14.

Embryonic microglia maintain the brain's cortical fault lines.

Gupte, Anushree S; de Soysa, T Yvanka; Stevens, Beth.

Trends Immunol ; 45(5): 327-328, 2024 May.

Artículo en Inglés | MEDLINE | ID: mdl-38664101

15.

Redefining microglia states: Lessons and limits of human and mouse models to study microglia states in neurodegenerative diseases.

Yvanka de Soysa, T; Therrien, Martine; Walker, Alicia C; Stevens, Beth.

Semin Immunol ; 60: 101651, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-36155944

16.

A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding.

Li, Tao; Chiou, Brian; Gilman, Casey K; Luo, Rong; Koshi, Tatsuhiro; Yu, Diankun; Oak, Hayeon C; Giera, Stefanie; Johnson-Venkatesh, Erin; Muthukumar, Allie K; Stevens, Beth; Umemori, Hisashi; Piao, Xianhua.

EMBO J ; 39(16): e104136, 2020 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-32452062

17.

Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.

Scott-Hewitt, Nicole; Perrucci, Fabio; Morini, Raffaella; Erreni, Marco; Mahoney, Matthew; Witkowska, Agata; Carey, Alanna; Faggiani, Elisa; Schuetz, Lisa Theresia; Mason, Sydney; Tamborini, Matteo; Bizzotto, Matteo; Passoni, Lorena; Filipello, Fabia; Jahn, Reinhard; Stevens, Beth; Matteoli, Michela.

EMBO J ; 39(16): e105380, 2020 08 17.

Artículo en Inglés | MEDLINE | ID: mdl-32657463

18.

CSMD1 regulates brain complement activity and circuit development.

Baum, Matthew L; Wilton, Daniel K; Fox, Rachel G; Carey, Alanna; Hsu, Yu-Han H; Hu, Ruilong; Jäntti, Henna J; Fahey, Jaclyn B; Muthukumar, Allie K; Salla, Nikkita; Crotty, William; Scott-Hewitt, Nicole; Bien, Elizabeth; Sabatini, David A; Lanser, Toby B; Frouin, Arnaud; Gergits, Frederick; Håvik, Bjarte; Gialeli, Chrysostomi; Nacu, Eugene; Lage, Kasper; Blom, Anna M; Eggan, Kevin; McCarroll, Steven A; Johnson, Matthew B; Stevens, Beth.

Brain Behav Immun ; 119: 317-332, 2024 Mar 27.

Artículo en Inglés | MEDLINE | ID: mdl-38552925

19.

Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages.

Schafer, Dorothy P; Stevens, Beth.

Immunity ; 42(4): 600-2, 2015 Apr 21.

Artículo en Inglés | MEDLINE | ID: mdl-25902477

20.

A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis.

Mifflin, Lauren; Hu, Zhirui; Dufort, Connor; Hession, Cynthia C; Walker, Alec J; Niu, Kongyan; Zhu, Hong; Liu, Nan; Liu, Jun S; Levin, Joshua Z; Stevens, Beth; Yuan, Junying; Zou, Chengyu.

Proc Natl Acad Sci U S A ; 118(13)2021 03 30.

Artículo en Inglés | MEDLINE | ID: mdl-33766915

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Early Alzheimer's disease pathology in human cortex involves transient cell states.

GABA-receptive microglia selectively sculpt developing inhibitory circuits.

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

A Milieu Molecule for TGF-ß Required for Microglia Function in the Nervous System.

Microglia and the Brain: Complementary Partners in Development and Disease.

GABA-receptive microglia selectively sculpt developing inhibitory circuits.

Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts.

Shedding light on glioma growth.

Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion.

Immune Signaling in Neurodegeneration.

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes.

Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.

Neuron-Glia Signaling in Synapse Elimination.

Embryonic microglia maintain the brain's cortical fault lines.

Redefining microglia states: Lessons and limits of human and mouse models to study microglia states in neurodegenerative diseases.

A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding.

Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia.

CSMD1 regulates brain complement activity and circuit development.

Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages.

A RIPK1-regulated inflammatory microglial state in amyotrophic lateral sclerosis.